Profile

DOS is a proven chemistry synthesis approach that generates compounds for challenging drug targets. DOS accesses novel chemical space, distinct from other compound libraries available commercially or in Pharma corporate archives, providing clear intellectual property and freedom-to-operate.

CS-Map computational platform allows detailed small molecule fragment-based interrogation of protein folds and an understanding of small molecule binding sites across entire protein families. CS-Map enables discovery and modeling of such protein “hot spots”, including allosteric regulatory sites and protein-protein interaction sites.